England look like they have a new permanent manager in Gareth Southgate, after his 3-0 victory over Scotland last Friday.
Avoiding an embarrassing defeat at the hands of Spain is a must at Wembley and the Spaniards will be provide England's toughest test yet, since their defeat to Iceland at Euro 2016.
The Three Lions secured a narrow 1-0 win over La Roja when these two met last at Wembley in 2011.
England have not conceded a goal in four games since the Euros, but have failed to brush aside minnows like Malta- winning by just two goals at home to the 164th ranked team.
Spain convincingly brushed aside Macedonia 4-0 in their last fixture, making that four wins in their previous five following their Euro 2016 exit.
Spain have scored 17 and conceded just once in these five games, but Liechtenstein and Macedonia failed to make it Euro 2016 and account for 12 of those goals.
Their toughest tests came away to Italy, where Spain secured a draw, and away to Belgium in a friendly, where Spain won 2-0.
Who to Draft First?
Both sides are stronger at the back than going forward and Southgate will look to not lose at home in his first big test as manager. Only one goal has breached both side's defences in nine games, so look to avoid drafting forwards.
Instead, draft ball-playing defenders like John Stones. The Manchester City youngster has scored 100+ points in his last four games for England! Time a Pass Master or Defensive Rock correctly and you could earn a load of points.
Who to Avoid?
Avoid wingers and forwards on both sides but particularly England's as Vardy, Rashford and Lingard don't get involved in the build-up play as often as Adruiz, Mata and Silva will.
As previously mentioned, this game will see little to no goals and the play will be centred around the middle of the park. This means central midfielders and centre-backs will get lots of touches of the ball and rack up points but wingers and strikers will rarely see the ball.
Top Five Draft Picks
Stones, Lallana, Henderson, Koke, Wilshere.
As this game is expected to be close, timing your Power-ups will likely be the deciding factor in winning your game. For maximum effect, watch the game itself and play your Pass Master on your central midfielder or defender for x3 points when that team is in control of the game and passing it around. This is likely to happen for England between 30-45 mins into the game.